致力于免疫炎症在中枢神经退行性疾病中的作用及机制研究，近五年来以第一、共同第一或共同通讯作者在《Signal Transduction and Targeted Therapy》、《Cancer Research》、《Clinical and Translational Medicine》等著名期刊发表SCI论文12篇。先后荣获“超级博士后”、“优秀出站博士后”及“民革上海市委三八红旗手”等多项荣誉。主持国家自然科学基金青年、面上项目、中国博士后科学基金面上项目、太阳成集团自主原创基础研究项目、大型仪器设备开放测试基金等多项重要课题。参与国家自然科学基金面上项目、重点项目、重大研究计划、高端科技创新智库青年项目及上海市“科技创新行动计划”启明星项目、上海市浦江人才等多个高水平研究项目。主编《异常姿势评估与矫正》、参与编著《脊神经功能评估与解剖学分析》、《脑性瘫痪---现代外科治疗与康复》及《心理护理临床实践技能》等专著。
课题组代表性论文
1.Ge Gao#, Congcong Li#, Yizhao Ma#, Zhanping Liang#, Yun Li, Xiangyu Li, Shengyang Fu, Yi Wang, Xiaohuan Xia*, Jialin C. Zheng*. Neural stem cell-derived extracellular vesicles mitigate alzheimer’s disease-like phenotypes in a preclinical mouse model, Signal Transduction and Targeted Therapy, 2023 Jun, 14;8(1):228.
2.Ge Gao#, Congcong Li#, Jie Zhu#, Shiyang Sheng, Zhanping Liang, Shengyan Fu, Xiangyu Li, Yiyan Sun, Yi Wang, Xuanran Feng, Xiaohuan Xia*, Jialin C. Zheng*, Induced neural stem/progenitor cell-derived extracellular vesicles promote recovery post stroke, Clinical and Translational Medicine, 2022, 12(6): e936.
3.Yi Tian#, Ge Gao#, Jiapei Dai*, Severe tauopathy and axonopathy in the medulla oblongata in Alzheimer’s disease implicate the changes in autonomic nervous function, Journal of Chemical Neuroanatomy, 2022, 102105.
4.Yaru Xu#, Ge Gao#, Xiaoru Sun, Qidong Liu*, Cheng Li*, ATPase Inhibitory Factor 1 Is Critical for Regulating Sevoflurane-Induced Microglial Inflammatory Responses and Caspase-3 Activation, Frontiers in Cellular Neuroscience, 2021, 15:483.
5.Ge Gao#, Congcong Li#, Jie Zhu#, Yi Wang, Yunlong Huang, Shu Zhao, Shiyang Sheng, Yu Song, Chenhui Ji, Chunhong Li, Xiaoyu Yang, Ling Ye, Xinrui Qi, Yanyan Zhang, Xiaohuan Xia*, Jialin C. Zheng*, Glutaminase 1 regulates neuroinflammation after cerebral ischemia through enhancing microglia activation and pro-inflammatory exosome release. Frontiers in Immunology, 2020, 11:161.
6.Ge Gao#, Shu Zhao#, Xiaohuan Xia#, Chunhong Li, Congcong Li, Chenhui Ji, Shiyang Sheng, Yalin Tang, Jie Zhu, Yi Wang*, Yunlong Huang*, Jialin C. Zheng*, Glutaminase C regulates microglia activation and pro-inflammatory exosome release: relevance to the pathogenesis of Alzheimer’s disease. Frontiers in Cellular Neuroscience, 2019, 13:264.
7.Qiushi Wang#, Ge Gao#, Tianshun Zhang#, Ke Yao, Hanyong Chen, Mi Hee Park, Hiroyuki Yamamoto, Keke Wang, Weiya Ma, Margarita Malakhova, Ann M Bode, Zigang Dong*, TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis. Cancer Research, 2018, 78: 3982-3994.
8.Ge Gao#, Tianshun Zhang#, Qiushi Wang, Kanamata Reddy, Hanyong Chen, Ke Yao, Keke Wang, Eunmiri Roh, Tatyana Zykova, Weiya Ma, Joohyun Ryu, Clara Curiel-Lewandrowski, David Alberts, Sally E. Dickinson, Ann M. Bode, Ying Xing*, Zigang Dong*, ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK. Molecular Cancer Therapeutics, 2017. 16(9): p. 1843-1854.
