肺血管疾病相关的发病因素，潜在发病机制和干预治疗的相关研究

Research on the pathogenic factors, underlying mechanisms, and potential intervention treatments related to pulmonary vascular disease

1. 中国医药协会呼吸病运动康复分会常务委员

2. 上海神经学会会员

3. 中国医药协会智能心血管病专业委员会委员

4. 中国研究型医院学会心脏康复专业委员会委员

5. 缺氧与呼吸专业委员会委员

1. Executive Committee Member of Respiratory Disease Exercise Rehabilitation Branch of China Medical Association

2. Member of Shanghai Neurological Society

3. Member of the Intelligent Cardiovascular Disease Professional Committee of the Chinese Medical Association

4. Member of the Cardiac Rehabilitation Professional Committee of the Chinese Research Hospital Association

5. Member of the Hypoxia and Respiratory Professional Committee

共发表SCI 论文 100余篇，包括AJRCCM，ERJ，TN，Advance Science等期刊；承担国家自然基金，上海市自然基金及其他10余项纵向科研课题，并以骨干身份参与多项重大研究计划等项目；已授权专利 4 项。

代表文章如下：

1.Ping Yuan, Jinling Li, Jianhui Liu, Hongting Liu, Sugang Gong, Lan Wang, Jinming Liu, Congcong Li, Yi Wang, Xiaohuan Xia, and Jialin C. Zheng. Cognitive dysfunction in patients with pulmonary hypertension. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1289-1293.

2.Ping Yuan, Jinling Li, Jianhui Liu, Hongting Liu, Sugang Gong, Lan Wang, Jinming Liu, Congcong Li, Yi Wang, Xiaohuan Xia, and Jialin C. Zheng. Cognitive dysfunction in patients with pulmonary hypertension. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1289-1293.

代表科研项目如下：

国家自然科学基金面上项目，METTL1介导m7G甲基化异常修饰在肺动脉高压内皮细胞糖代谢重编程中的作用及机制研究，主持，项目编号：82370057， 2024.01-2027.12.

上海市自然科学基金面上项目，外泌体circCRIM1介导周细胞-内皮细胞间通讯参与肺动脉高压肺血管重构的作用研究, 主持，项目编号：21ZR1453800，直接经费：20万元，2021.07-2024.06.

国家自然科学基金面上项目， CircRNA_00286与miRNAs相互对话调控肺动脉高压右心室心肌细胞程序性死亡的机制研究，主持，项目编号：81870042，2019.01-2022.12.

国家自然科学基金青年项目，Arhgap24介导雌二醇调节肺动肺动脉平滑肌细胞增殖差异效应的机制，主持，项目编号：81500040，2016.01-2018.12.

Published over 100 SCI papers, including AJRCCM, ERJ, TN, Advance Science, and other journals; Undertook more than 10 longitudinal research projects funded by the National Natural Science Foundation of China, the Shanghai Natural Science Foundation, and others, and participated in multiple major research projects as a key member; We have been granted 4 patents.

The representative papers are as follows:

1. Ping Yuan, Jinling Li, Jianhui Liu, Hongting Liu, Sugang Gong, Lan Wang, Jinming Liu, Congcong Li, Yi Wang, Xiaohuan Xia, and Jialin C. Zheng. Cognitive dysfunction in patients with pulmonary hypertension. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1289-1293.

2. Ping Yuan, Jinling Li, Jianhui Liu, Hongting Liu, Sugang Gong, Lan Wang, Jinming Liu, Congcong Li, Yi Wang, Xiaohuan Xia, and Jialin C. Zheng. Cognitive dysfunction in patients with pulmonary hypertension. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1289-1293.

The representative research projects are as follows:

1. National Natural Science Foundation of China General Project, Role and mechanism of METTL1 mediated m7G methylation abnormal modification in glucose metabolism reprogramming of pulmonary artery endothelial cells, project leader, Number: 82370057, 2024.01-2027.12.

2. Shanghai Natural Science Foundation General Project, Role of extracellular exsomal circCRIM1 in mediating cell communication between pericyte and pulmonary artery endothelial cells in pulmonary vascular remodeling of pulmonary arterial hypertension, project leader, number: 21ZR1453800, 2021.07-2024.06.

3. General Project of National Natural Science Foundation of China, Study on the mechanism of CircRNA_00286 and miRNAs dialogue in regulating programmed death of right ventricular cardiomyocytes in pulmonary hypertension, Project Leader, Project Number: 81870042, 2019.01-2022.12.

4. National Natural Science Foundation of China Youth Project, Mechanism of arhgap24 mediating estradiol mediated differential effect on pulmonary arterial smooth muscle cell proliferation, Project Leader, Project Number: 81500040, 2016.01-2018.12.