主攻内分泌及代谢病。主要的研究兴趣是肥胖相关性代谢紊乱、糖尿病慢性并发症（糖尿病性血管和神经病变）及糖脂代谢紊乱的临床及基础研究。

My specialty is Endocrine and Metabolic Diseases. My major research interesting is focus on basic and clinical research of obesity-related metabolic disorders、chronic complications of diabetes (diabetic vascular and neuropathy disease) and glucose and lipid metabolism disorder.

01/2015-04/2016 ，Children’s Hospital of Pittsburgh of UMPC, Visiting scholar，美国匹兹堡大学儿童医学中心 访问学者

12/2010-present，Department of Endocrinology and Metabolism, Tenth People’s Hospital of Tongji University, Associate Chief Physican，太阳成集团附属第十人民医院内分泌及代谢科副主任医师

Member of Shanghai Youth Diabetes Association，上海市糖尿病学分会青年委员

Member of Shanghai Diabetes Association Education And Training Group，上海市糖尿病学分会教育与管理学组成员

Member of Shanghai Diabetes Association Metabolic Syndrome Group，上海市糖尿病学分会代谢综合征学组成员

从事大量科研及临床工作。过去5年，先后在核心及SCI期刊发表基础、临床相关论著20余篇，发表SCI文章12篇（其中第一及通讯作者SCI文章4篇，美国ADA年会收录摘要3篇）。参与主持多项国家自然科学基金。获得“上海浦江人才计划”资助。

I have done great research work as well as my clinic work. For past 5 years, I have published 20 scientific papers related to basic research and clinical practice. 12 of them are published in SCI journal. And I was first and corresponding author of 4 papers. In addition, I have published 3 abstracts in international conferences including the U.S. ADA Conference. I have been involved in several National Natural Science Foundation grants and received funding from “Shanghai Pujiang Talent Program”.PUBLICATIONS

（文章）：1. Cheng X, Yamauchi J, Lee S, Zhang T, Gong Z, Muzumdar R, Qu S and Dong HH. APOC3 Is Not a Predisposing Factor for Fat-Induced Nonalcoholic Fatty Liver Disease in Mice. J Biol Chem. 2017, Jan 23. pii: jbc.M116.765917. doi: 10.1074/jbc.M116.765917. （第一作者）

2. Liu YZ, Cheng X, Zhang T, Lee S, Yamauchi J, Xiao X, Gittes G, Qu S, Jiang CL, Dong HH. Effect of Hypertriglyceridemia on Beta Cell Mass and Function in ApoC3 Transgenic Mice. J Biol Chem. 2016 Jul 8;291(28):14695-705. doi: 10.1074/jbc.M115.707885. Epub 2016 May 11. （共同第一作者）

3. Li L, Rampersad S, Wang X, Cheng X, Qu S. Serum irisin concentrations were increased after transient continuous subcutaneous insulin infusion in type 2 diabetes mellitus patients. Diabetes Res Clin Pract. 2016 Mar;113:44-7. doi: 10.1016/j.diabres.2016.01.030. （通讯作者）

4. Cheng X, Gao W, Dang Y, Liu X, Li Y, Peng X, Ye X. Both ERK/MAPK and TGF-Beta/Smad signaling pathways play a role in the kidney fibrosis of diabetic mice accelerated by blood glucose fluctuation. J Diabetes Res. 2013;2013:463740. doi: 10.1155/2013/463740.（第一作者）

5. Ye X, Cheng X, Liu L, Zhao D, Dang Y. Blood glucose fluctuation affects skin collagen metabolism in the diabetic mouse by inhibiting the mitogen-activated protein kinase and Smad pathways. Clin Exp Dermatol. 2013 Jul;38(5):530-7. doi: 10.1111/ced.12002.

6. Sheng H, Sheng CJ, Cheng XY, Zhang G, Lee KM, Leung KS, Qu S, Qin L. Pathomorphological changes of bone marrow adipocytes in process of steroid-associated osteonecrosis. Int J Clin Exp Pathol. 2013 May 15;6(6):1046-50.

7. Bu L, Chang X, Cheng X, Yao Q, Su B, Sheng C, Qu S. Activated central galanin type 1 receptor alleviated insulin resistance in diabetic rat muscle.J Neurosci Res. 2016 Oct;94(10):947-55. doi: 10.1002/jnr.23775. Epub 2016 Jul 13.

8. Huang Y, Yang J, Li Y, Chen J, Song K, Wang X, Bu L, Cheng X, Wang J, Qu S. FGF21 Is Associated with Acanthosis Nigricans in Obese Patients. Int J Endocrinol. 2016;2016:1658062. doi:10.1155/2016/1658062.

9. Huang Y, Chen J, Yang J, Song K, Wang X, Cheng X, Qu S. Evaluation of depressive symptoms in obese patients with or without acanthosis nigricans. Hormones (Athens). 2015 Jul-Sep;14(3):417-24. doi: 10.14310/horm.2002.1575.

10. Zhang M, Li Y, Cui W, Yang P, Li H, Sheng C, Cheng X, Qu S.THE CLINICAL AND METABOLIC CHARACTERISTICS OF YOUNG-ONSET KETOSIS-PRONE TYPE 2 DIABETES IN CHINA. Endocr Pract. 2015 Dec;21(12):1364-71. doi: 10.4158/EP15778.OR.

11. Song K, Han Y, Zhang L, Liu G, Yang P, Cheng X, Bu L, Sheng H, Qu S. ATP Synthase β-Chain Overexpression in SR-BI Knockout Mice Increases HDL Uptake and Reduces Plasma HDL Level.Int J Endocrinol. 2014;2014:356432.

12. Cui R, Su B, Sheng C, Cheng X, Yang P, Bu L, Li H, Wang J, Sheng H, Qu S. Total osteocalcin in serum predicts testosterone level in male type 2 diabetes mellitus. Int J Clin Exp Med. 2014 Apr 15;7(4):1145-9.