帕金森病的基础与临床研究 Basic and clinical research on the pathogenesis, diagnosis and treatment of Parkinson´s disease
国际帕金森与运动障碍协会会员
中华医学会神经病学分会神经调控协作组委员
Member of International Parkinson and Movement Disorder Society
Member of the Neuromodulation Collaborative Group, Neurology Branch, Chinese Medical Association (2021)
发表国内外论文30余篇，主持国家自然科学基金、国家重点研发计划子课题等多个项目的研究，作为主要参与者完成了中国第一个获得国家卫健委备案的干细胞治疗帕金森病的临床研究。获得科研经费200万元。
More than 30 papers have been published in the domestic and foreign journals. Presided over several projects/sub-project supported by the National Key R&D Program of China，National Natural Science Foundation of China and Shanghai Shenkang Hospital Development Cente. And wined 2 million yuan funding support.
获得课题
1 国家自然科学基金，SIRT2影响腰髓中间神经元诱发MPTP小鼠步态异常的作用机制研究。2020.1-2023.12 经费55万 负责人
国家重点研发项目子课题，不自主运动精细分型体系及全程化管理模式研究。2018.10-2020.12 经费57万 负责人
2 中央高校基本科研业务费专项资金-学科交叉类（重点项目），环境毒素诱发肠神经系统帕金森病样病理改变的机制研究2018.10-2020.9 经费60万，负责人
3 申康中心临床研究培育项目: 基于SPECT显像判定帕金森病姿势异常痉挛责任肌肉的新技术研究 "2018.11.15 -2021.11.14日 经费30万 负责人
4 医院临床研究培育重点项目 131I-MIBG唾液腺显像与帕金森病的相关性研究 2019.1-2021.12 经费25万 负责人
5 人源性干细胞治疗帕金森病人源神经干细胞治疗早发型帕金森病伴运动并发症的安全性与初步有效性评价。2019.4-2021.12 经费76万 第二负责人
近期发表文章
1 Hong Ronghua…, Guan Qiang, Jin Lingjing. A summary index derived from Kinect to evaluate postural abnormalities severity in Parkinson's Disease patients. NPJ Parkinsons Dis. 2022; 8 (1): 96. doi: 10.1038/s41531-022-00368-x(并列通讯作者).
2 Yijing He…, Qiang Guan, Lingjing Jin, Changes of T lymphocyte subpopulations and their roles in predicting the risk of Parkinson’s disease. Journal of Neurology, (2022) https://doi.org/10.1007/s00415-022-11190-z（并列通讯作者）
3 Zhang JX…，Guan Q, Jin LJ. MANF inhibits α-synuclein accumulation through activation of autophagic pathways. Oxid Med Cell Longev，（2022）2022:7925686. doi: 10.1155/2022/7925686. eCollection（并列通讯作者）
4 Zhuoyu Zhang…, Qiang Guan，LingJing Jin. Automated and accurate assessment for postural abnormalities in patients with Parkinson’s disease based on Kinect and machine learning. Journal of NeuroEngineering and Rehabilitation, (2021) 18:169. https://doi.org/10.1186/s12984-021-00959-4(并列通讯作者)
5 Guan Qiang，Wang Xijin，Jian Yanyan，et al，RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways.，Neurochem Res，2017.2.01，42（2）：572-582（第一作者）
