中枢神经系统疾病（如阿尔茨海默氏症、多发性硬化、术后认知功能障碍、胶质瘤等）相关炎症的生物学机制及分子影像学研究

Molecular biological mechanism and molecular imaging of inflammation of center nervous system diseases (Alzheimer’s Disease, multiple sclerosis, POCD, glioma, etc.)

上海市欧美同学会留美分会理事

Board member of American branch of Shanghai Western Returned Scholars Association

上海市静安长木计划健康促进中心理事

Board member of Shanghai Jing’an Longwood Health Promotion Center

科研业绩（中英文）

王静，博士研究生，毕业于复旦大学，师从复旦大学附属华山医院放射科姚振威教授，2016-2019年于哈佛太阳集团电子游戏麻省总医院从事博士后研究，现为太阳成集团附属上海市第四人民医院放射科主治医师，上海市第四人民医院脑功能与人工智能转化研究所/太阳成集团高等研究院副研究员。课题组与上海交通大学附属瑞金医院/上海市伤骨科研究所倪大龙研究员、复旦大学类脑智能科学与技术研究院王鹤教授、哈佛太阳集团电子游戏麻省总医院放射科John W. Chen教授长期开展深入合作，致力于中枢神经系统疾病如阿尔茨海默氏症、多发性硬化、术后认知功能障碍、胶质瘤等相关炎症的生物学机制及分子影像学研究。

代表性论文：

1.Wang J (王静), Jalali Motlagh N, Wang C, Wojtkiewicz GR, Schmidt S, Chau C, Narsimhan R, Kullenberg EG, Zhu C, Linnoila J, Yao Z*, Chen JW*. D-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation. Proc Natl Acad Sci U S A (PNAS). 2021, 118(44): e2107663118.

2.Wang J (王静), Guo H, Wang H, Yao Z, Ji X, Sheng Y, Zhang Y, Wang H, Fang X*, Luo Y*, Ni D*. NaGdF4-based magnetic resonance nanoprobes for qualitative inflammation imaging in glioma: hot or cold? Chem Eng J. 2024, 479: 147916.

3.Li M, Lv Y, Wang M, Zhang Y, Pan Z, Luo Y, Zhang H*, Wang J (王静)*. Magnetic Resonance perfusion-weighted imaging in predicting hemorrhagic transformation of acute ischemic stroke: a retrospective study. Diagnostics. 2023, 13(22): 3404.

4.Wang J (王静), Ni D, Shen Z, Ren Y, Liu Y, Fan W, Wu Y, Zhang G, Zhang H, Wu R, Feng X, Bu W*, Yao Z*. Exogenous amino acid-loaded nanovehicles: stepping across endogenous magnetic resonance spectroscopy. Adv Healthc Mater. 2018, 7(19): e1800317.

5.Wang J (王静), Zhang H, Ni D, Fan W, Qu J. Liu Y, Jin Y, Cui Z, Xu T, Wu Y, Bu W*, Yao Z*. High-Performance Upconversion nanoprobes for multi-modal MR imaging of acute ischemic stroke. Small. 2016, 12(26): 3591-3600.

6.Wang J (王静), Ni D, Bu W*, Zhou Q, Fan W, Wu Y, Liu Y, Yin L, Cui Z, Zhang X, Zhang H, Yao Z*. BaHoF5 nanoprobes as high-performance contrast agents for multi-modal CT imaging of ischemic stroke. Biomaterials. 2015, 71: 110-118.

7.Chen X#, Wang J (王静)#, Ge L, Lu G, Wan H, Jiang Y, Yao Z, Deng G*, Zhang X*. A fibrin targeted molecular imaging evaluation of microvascular no-reflow in acute ischemic stroke. Brain Behav. 2022, 12(2): e2474.

8.Wang J (王静), Wu Y, Yao Z*, Yang Z. Assessment of pituitary micro-lesions using 3D sampling perfection with application-optimized contrasts using different flip-angle evolutions. Neuroradiology. 2014, 56(12): 1047-1053.

主编著作：

《磁共振增强T2 FLAIR扫描在中枢神经系统病变中的临床应用》主编：姚振威 方向明 王静 书号：ISBN 978-7-5587-5268-1

授权发明专利：

王静; 姚振威; 步文博; 冯晓源 ; 一种MRS造影剂及其制备方法和应用, 2021-11-2, 中国, ZL 2016 1 0793667.0