课题：主持国家级课题1项，上海市科委课题1项
奖项：省部级一等奖（前3）、市局级二等奖（前5）
论文：发表第一或通讯作者SCI论文9篇，累计影响因子>89分，最高41.444分 （近3年）
课题与成果
国家级：国家自然科学基金资助项目（No.82172696）：circBRD9调控 miR-28-5p/CD155/TIGIT诱导非小细胞肺癌NK细胞耗竭导致PD-1抗体耐药机制的研究（主持）
省部级：上海市自然科学基金资助项目（No.19ZR1441900）：长链非编码RNA DSCAM-AS1调控非小细胞肺癌对PD-1抗体耐药的分子机制研究（主持）
地市级：浦东新区中青年业务骨干培训计划 （主持）
获 奖：省部级科技进步一等奖：肺癌发病机制研究及早期诊断关键技术和个体化治疗策略推广应用
上海市浦东新区科技进步二等奖：Sp1/VEGF基因表达与胃癌靶向治疗疗效相关性临床研究
科研论文
1. Peng-Fei Zhang, Xu Pei, Ke-Sang Li, Fei Wang, Jing Wu，Xue-Mei Zhang. Circular RNA circFGFR1 promotes progression and anti-PD-1 resistance by sponging miR-381-3p in non-small cell lung cancer cells. Molecular Cancer.2019,18:179. (IF：41.444)
2. Peng Fei Zhang, Jing Wu, Yin Wu, Wei Huang, Zhao Ru Dong, Xue Mei Zhang. The lncRNA SCARNA2 mediates colorectal cancer chemoresistance through a conserved microRNA-342 -3p target sequence. J Cell Physiol. 2019, 234(7):10157-10165. (IF：6.513)
3. Fei Wang, Hongxia Ma, Zhaoguo Liu, Wei Huang, Xiao jing Xu, Xuemei Zhang. α-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice. BiomedPharmacother.2017.08.(92):672-680. (IF：7.419)
4. Jun Liang, Jing Wu, Fei Wang, Xuemei Zhang. Semaphoring 4D is required for the induction of antioxidant stress and anti inflammatory effects of dihydromyricetin in colon cancer. International Immunopharmacology. 2019.02.(67):220-230. (IF：5.714)
5. Bai-Quan Qiu, Xia-Hui Lin, Xu-Dong Ye1, Wei Huang, Xu Pei, Lu-Lu Sheng, Xue-Mei Zhang, Peng-Fei Zhang, Yong-Bing Wu. Long non-coding RNA PSMA3-AS1 promotes malignant phenotypes of esophageal cancer by modulating the miR-101/EZH2 axis as a ceRNA. AGING. 2020, Vol. 12, No. 2:1843-1856. (IF：5.682)
6. Bai Quan Qiu, Peng Fei Zhang, Dian Xiong ,Jian Jun Xu, Xue Mei Zhang, Yong B
