上海市第十人民医院病理科带组组长、生物样本库负责人 （Leader of the pathology department and head of Bio-bank, Shanghai Tenth People
先后主持国家自然基金和上海市自然基金等课题，科研经费累计200余万元，在相关领域发表SCI论文15篇，其中以第一作者或通讯作者在Signal Transduction Targeted Therpy、Nature communications等杂志上发表6篇论文。
I have presided over projects such as the National Natural Science Foundation of China and the Shanghai Natural Science Foundation, with a total of more than 2 million yuan in scientific research funds, and published 15 SCI papers in related fields, of which 6 have been published as the first author or corresponding author in journals such as Signal Transduction Targeted Therpy and Nature communications. 代表性研究成果（Representative papers）：
1. Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer. Sig Transduct Target Ther 6, 398 (2021).
2. Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling, Cancer Res, 81 (2021) 4485-4498.
3. A newly developed PCR-based method revealed distinct Fusobacterium nucleatum subspecies infection patterns in colorectal cancer, Microb Biotechnol, 14 (2021) 2176-2186.
4. Integrin alpha5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker, Mol Oncol, 13 (2019) 2697-2714.
5. VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2. Nature communications 8 （2017）, 15337.
6. Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress. Free Radic Biol Med 93（2016） 165-176.
