目前已参与多项生物纳米及肿瘤免疫相关领域相关研究工作，掌握乳腺癌及其它肿瘤免疫治疗及纳米材料应用领域的最新研究进展，熟悉免疫细胞的分离培养，掌握小鼠乳腺原位荷瘤鼠模型的建立，及分子生物学实验等技术。本课题申请者承担国家自然科学基金、浦东新区卫计委卫生科研青年项目及优秀青年人才培养行动计划等多项科研课题，已在纳米生物医学相关领域SCI及核心期刊杂志发表文献数篇。协助培养多名硕士生及博士生。具备临床及科研工作的能力及基础。
At present, she has participated in multiple
research work in the fields of bio-nano and tumor immunization,
mastered the latest research progress of the immunotherapy and nanomaterial
application in breast cancer, and been familiar with the isolation and culture
of immune cells, establishment of tumor-bearing mouse model and molecular
biology experiments technologies. She has also undertaken a number of scientific
research projects such as the National Nature Science Foundation of China, the
Project of Excellent Youth Training of Tongji University, and the Youth Project
of Health and Family Planning Committee of Pudong New Area and so on. Several articles
have been published in SCI and core journals related to nanobiomedicine. She has
assisted in the postgraduate training of the department of Breast Cancer
Center, and possessed the clinical and scientific research ability.
代表性论文（Representative paper）：
1.
Shujing Liang,
Chao Li, Chunlei Zhang, etc.CD44v6 Monoclonal Antibody-Conjugated Gold
Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy
of Gastric Cancer Stem-like Cells [J]. Theranostic,
2015, 5(9): 970-984.(IF:8.854)
2. Yonglin
Lu, Yain Ma, Chan Feng, Donglei Zhu, Jie Liu, Lv Chen, Shujing Liang*,
Chunyan Dong*. Co-delivery of
Cyclopamine and Doxorubicin Mediated by Bovine Serum Albumin Nanoparticles
Reverses Doxorubicin Resistance in Breast Cancer by Down-regulating
P-glycoprotein Expression [J].
J Cancer, 2019,10(10):2357-2368. (IF:3.182)
3. Chao
Li, Shujing Liang, Chunlei Zhang, Yanlei Liu, Meng Yang, Jingpu Zhang,
Xiao Zhi, Fei Pan, Daxiang Cui. Allogenic dendritic cell and tumor cell fused
vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric
cancer [J]. Biomaterial, 2015,
54, 177-187.(IF: 8.557
)
4. Chao Li, Ji Yang, Can
Wang, Shujing Liang, Fei Pan, Chunlei Zhang, Feng Chen, Hualin Fu, Kan
Wang and Daxiang Cui. BRCAA1 antibody-and Her2 antibody-conjugated amphiphilic
polymer engineered CdSe/ZnS quantum dots for targeted imaging of gastric cancer[J].
Nanoscale Res Lett, 2014, 9, 1-13. (IF:2.779)
5. Zhang C, Li C, Liu Y,
Jingpu Zhang, Chenchen Bao, Shujing Liang, Qing Wang, Yao Yang, Hualin
Fu, Kan Wang, and Daxiang Cui. Gold Nanoclusters‐Based Nanoprobes for
Simultaneous Fluorescence Imaging and Targeted Photodynamic Therapy with
Superior Penetration and Retention Behavior in Tumors[J]. Advanced Functional
Materials, 2015, 25, 1314–1325 (IF:11.805)
6. Liang Xu, Xiaobo Wu, Chun
Hu, Zhiying Zhang, Le Zhang, Shujing Liang, Yingchun Xu, Fengchun Zhang.
A meta-analysis of combination therapy versus single-agent therapy in
anthracycline- and taxane-pretreated metastatic breast cancer: results from
nine randomized Phase III trials. Onco Targets Ther. 2016, Jul
4;9:4061-74(IF:2.272).
7. Liang Xu, Le Zhang, Chun
Hu, Shujing Liang, Xiaochun Fei, Ningning Yan, Yanyun Zhang, Fengchun
Zhang. WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and
metastasis of breast cancer stem cells. Int J Oncol. 2016 Mar;48(3):1175-86(IF:
2.371).
8. Chun Hu, Liang Xu, Shujing
Liang, Zhiying Zhang, Yanyun Zhang, Fengchun Zhang. Lentivirus-mediated
shRNA targeting Nanog inhibits cell proliferation and attenuates cancer stem
cell activities in breast cancer. J Drug Target. 2016;24(5):422-32(IF:2.821).
9. 梁淑静，徐丽敏等.疣状表皮发育不良的共聚焦激光扫描显微镜下表现[J]. 中国皮肤性病学杂志，2011,25(3):231-233.2
9. 梁淑静，徐丽敏等. 扁平苔藓的共聚焦激光扫描显微镜特征表现[J].临床皮肤科杂志，2011,40（3）：139-141.
